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A Principal Investigator (PI) is an individual responsiblefor the study at a single recruiting centre, so a multicentre study would haveseveral PIs.

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Screening should start at 45 years of age in theabsence of other risk factors. The current literature often definesorthopedic infections as “osteoarticular,” suggesting that diagnosis and treatment of boneand joint infection would be similar. Results of this trial may help establish aclinical role for Lp-PLA screening.

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